Senior Scientist

Senior Scientist
Oxford -| On-site | Start-up Biotechnology Company

Talentmark is partnering with an biotech start-up developing next-generation gene therapies for severe genetic diseases. With a highly collaborative scientific team and innovative platform technologies, the company is advancing cutting-edge preclinical programmes focused on delivering transformative therapies to patients with high unmet need. This is a site-based position located at Oxford.-

As part of their continued growth, they are seeking a Senior Scientist with a strong track record of managing outsourced pre-clinical studies within the biotech industry.-This is an excellent opportunity for someone who enjoys working in a fast-paced, science-driven environment where they can combine scientific leadership, CRO oversight, and hands-on laboratory expertise.

The Opportunity
You will play a key role in driving preclinical in vivo studies through external CRO partnerships, supporting the progression of gene therapy programmes from discovery through translational development.-The successful candidate will bring proven experience managing CROs, overseeing in vivo studies, and hands-on wet lab experience collaborating cross-functionally within a biotech setting.

Key Responsibilities

• Lead the design, oversight, and interpretation of preclinical in vivo studies with external CRO partners
• Manage CRO relationships across study planning, timelines, budgets, protocol review, and data delivery
• Act as the internal scientific lead for animal model studies including efficacy, biodistribution, and toxicology
• Maintain hands-on involvement in molecular and cellular biology workflows
• Support the design and optimisation of gene expression constructs and vector development activities
• Contribute to data analysis, project planning, and scientific reporting across multiple programmes

Your-Background:

• PhD in Molecular Biology, Gene Therapy, Immunology, Virology, Translational Medicine, or related discipline
• Proven biotech industry experience within preclinical or translational research environments
• Strong track record managing CRO-based in vivo studies
• Experience with histology, bioanalysis, or biodistribution studies
• Experience driving study execution to timelines
• Hands-on wet lab expertise in molecular and/or cell biology
• Strong scientific data interpretation and problem-solving skills
• Excellent project management abilities

Highly Desirable

• Experience within gene therapy, viral vectors, or advanced therapeutics
• Exposure to GLP toxicology or IND-enabling studies
• Background working with translational animal models

Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference (Apply online only) in all correspondence.

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