Senior Scientist Phage Display

CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a lab-based Senior Scientist position in the Protein Binder Discovery team based in Granta Park, Cambridge.Company: Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs in Japan and globally, focused on therapeutic areas in inflammation diseases, neurology and immunology.The Role: We are searching for an experienced phage display scientist to join the Protein Binders team, part of our Platform Technology division at Nxera Pharma. The successful candidate will use phage display expertise to identify and characterise protein binders against therapeutic membrane protein targets to enable structure determination and drug discovery efforts. The candidate will work in interdisciplinary teams in a project-centric fashion, with the aim of accelerating the development of life-changing medicines.The role will include the following responsibilities:Employing phage display technology to select protein binders against membrane protein targets Screening and validating hits using high-throughput assays e.g. ELISA formats, BLI, cell binding assaysAssay development for challenging targetsSubcloning of plasmid constructs for expression and protein engineering of antibody frameworksBiophysical evaluation of VHH hitsSharing your expertise, insights, and ideas with the team, and department to positively ..... full job details .....