About the RoleApplications are sought for an exciting opportunity within the Ciccarelli lab, within the Centre for Cancer Evolution, Barts Cancer Institute.We are seeking an independent, highly motivated computational Postdoctoral Research Assistant to lead on an established and successful research line aimed at understanding the role of the tumour immune microenvironment (TIME) in response to immunotherapy. This project stems from previous work where we showed that TIME composition determines response to immunotherapy (Bortolomeazzi Gastroenterology 2021) and identified a marker of this ideal TIME using a combination of spatial transcriptomics and immunostaining (Acha-Sagredo Cancer Cell 2025). In parallel, we developed computational methods for the analysis of spatial omics data (Bortolomeazzi Nature Comms 2022) and clustering of rare cell populations (Martens, Bioinformatics 2023).The post holder will have the main responsibilities of analysing genomics, transcriptomics and spatial transcriptomics and proteomics data and will be integrated within a team within our lab working on this large project.The Ciccarelli lab is highly collaborative and interdisciplinary and the ability to work in a team is essential.About YouThe successful candidate will be expected to have a PhD degree in biological or computational sciences or equivalent, with solid knowledge of computational coding applied to genomics. Significant research laboratory experience in genomic and transcriptomic ..... full job details .....