Executive Director, ADC tumor MDT Biomarker Lead

Executive Director, ADC tumor MDT Biomarker Lead – Oncology, Clinical Biomarkers at GSKOverviewAt GSK, we are committed to improving lives through innovative science and transformative medicines. As the Executive Director, ADC tumor MDT Biomarker Lead, you will play a pivotal role in shaping and implementing clinical biomarker strategies that inform clinical development and decision-making in collaboration with tumor-specific Medicine Development Teams (MDT). This matrix leadership role focuses on high priority programs within the Oncology portfolio and requires extensive experience in the application of clinical biomarkers and translational research within clinical development with the goal to inform right dose, right patient, right drug at the right time. You will lead matrix teams of Clinical Biomarker experts supporting individual trials and drive the creation and alignment of translational medicine strategies in support of ADC tumor-specific MDTs.Key ResponsibilitiesSubject matter expert in solid tumor or haematological tumor biology, disease progression and treatment options; accountable for the strategic design and oversight of implementation of Biomarker strategies associated with disease modalities related to drug development programsLeading tumor-specific ADC Biomarker Matrix teams to develop and execute clinical biomarker strategies for oncology programs in collaboration with internal and external stakeholders and with input from disease area teamsProviding input to clinical teams on biomarker-related elements of study trial design and conductSingle point accountable person for Clinical and Translational biomarker team at the MDT. Aligns biomarker strategy with TMP and leads interactions at the tumour-specific MDT(s), study teams and Protocol Review Forum; representing the MDTs at governance where neededManaging budgets and resources to deliver biomarker strategies effectivelyWorking with Translational Research teams to ensure alignment of preclinical and clinical biomarker strategiesPartnering with internal technology groups, Contract Research Organisations and collaborators to deliver clinically validated biomarker assays into clinical studiesCollaborating with Diagnostic leads to implement companion diagnostic strategies for validation, and regulatory approval of predictive biomarkersEnsuring alignment of biomarker outputs with data management, statistics, and modelling/simulation requirementsSupporting expansion of mechanism and disease understanding to generate insights for ADC indication expansion and marketing as requiredEnabling matrix team deliverables by ensuring evaluation of state-of-the-art platform technologies and incorporating innovative biomarkers into translational medicine plansCollaborating with clinical biomarker labs, clinical pharmacology leads and diagnostic lead, incorporating their input into clinical biomarker strategiesBasic QualificationsPhD in Oncology, Clinical Biomarkers, or Translational ResearchExtensive (>15 years) experience in Oncology clinical biomarkers and translational research within clinical developmentExperience in leading cross-functional teams and delivering strategic biomarker plansExperience in interpreting clinical biomarker data and assessing innovative platforms and biomarker technologies for clinical trialsExperience in senior stakeholder engagement supporting decision-making in drug developmentPreferred QualificationsExperience in global matrix leadership across multiple locationsFamiliarity with regulatory processes for companion diagnostics and predictive biomarkersAbility to anticipate future challenges and innovate solutions in biomarker strategiesExcellent communication, problem solving, and influencing skillsNote: This role may be hybridGSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under law.If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service ..... full job details .....