AI Protein Design Lead

Your new company You''ll be joining an exciting early-stage biotechnology company in London developing next-generation therapeutics. You''ll work in a highly collaborative environment at the intersection of computational biology, machine learning, structural biology, and protein engineering, helping to shape a core capability within the business.You''ll be joining them as they go into their next phase of growth, with plenty of opportunities for development and progression.Your new role This is a permanent position, based in London but with home working flexibility and you''ll report into the CTO.A key part of this role is driving the design and optimisation of therapeutic proteins using state-of-the-art AI models, physics-based approaches, and structural biology insights. Key responsibilities include:Applying AI-driven protein structure prediction and design tools to generate and prioritise novel protein variantsUsing energetic, structural, and conformational principles to improve protein stability, function, and design success ratesDesigning and optimising proteins and enzymes using computational modelling approachesApplying molecular dynamics simulations and related methods to understand protein behaviour and conformational landscapesTranslating computational designs into testable constructs for experimental validationWorking closely with internal scientists and external CRO partners to iterate and improve designs based on experimental resultsDeveloping and maintaining ..... full job details .....